{"study":"Abel 2021","category":"PSYCHIATRIC DISORDERS","outcome_disease":"Anxiety disorder","data_source":"Health Records","sample_size":11923105,"effect_type":"RR","effect":1.72,"TE":0.54033,"seTE":0.04271,"rate_control":0.0053,"follow_up_time":40,"mean_age":44,"reinfection":"no","disease_severity":"no","no_of_confounders":19,"uncertainty_of_confounders":"low","list_of_confounders":"race, ethnicity, smoking, BMI, comorbidities-cancer, cerebrovascular disease, chronic pulmonary disease, congestive heart failure, connective tissue disease, dementia, diabetes, HIV/AIDS, hemiplegia, myocardial infarction, liver disease, renal disease, peripheral vascular disease, posterior vitreous detachment, and peptic ulcer disease","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"low","ROB7":"low","ROB8":"low","ROB9":"low","ROB10":"high","ROB11":"low"} {"study":"Abel 2021","category":"PSYCHIATRIC DISORDERS","outcome_disease":"Psychosis","data_source":"Health Records","sample_size":11923105,"effect_type":"RR","effect":1,"TE":0.00268,"seTE":0.14332,"rate_control":0.0007,"follow_up_time":40,"mean_age":44,"reinfection":"no","disease_severity":"no","no_of_confounders":19,"uncertainty_of_confounders":"low","list_of_confounders":"race, ethnicity, smoking, BMI, comorbidities-cancer, cerebrovascular disease, chronic pulmonary disease, congestive heart failure, connective tissue disease, dementia, diabetes, HIV/AIDS, hemiplegia, myocardial infarction, liver disease, renal disease, peripheral vascular disease, posterior vitreous detachment, and peptic ulcer disease","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"low","ROB7":"low","ROB8":"low","ROB9":"low","ROB10":"high","ROB11":"low"} {"study":"Abel 2021","category":"PSYCHIATRIC DISORDERS","outcome_disease":"Any psychiatric disorder","data_source":"Health Records","sample_size":11923105,"effect_type":"RR","effect":1.69,"TE":0.52742,"seTE":0.03396,"rate_control":0.0085,"follow_up_time":40,"mean_age":44,"reinfection":"no","disease_severity":"no","no_of_confounders":19,"uncertainty_of_confounders":"low","list_of_confounders":"race, ethnicity, smoking, BMI, comorbidities-cancer, cerebrovascular disease, chronic pulmonary disease, congestive heart failure, connective tissue disease, dementia, diabetes, HIV/AIDS, hemiplegia, myocardial infarction, liver disease, renal disease, peripheral vascular disease, posterior vitreous detachment, and peptic ulcer disease","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"low","ROB7":"low","ROB8":"low","ROB9":"low","ROB10":"high","ROB11":"low"} {"study":"Abel 2021","category":"PSYCHIATRIC DISORDERS","outcome_disease":"Depressive disorders","data_source":"Health Records","sample_size":11923105,"effect_type":"RR","effect":1.81,"TE":0.59217,"seTE":0.04453,"rate_control":0.0047,"follow_up_time":40,"mean_age":44,"reinfection":"no","disease_severity":"no","no_of_confounders":19,"uncertainty_of_confounders":"low","list_of_confounders":"race, ethnicity, smoking, BMI, comorbidities-cancer, cerebrovascular disease, chronic pulmonary disease, congestive heart failure, connective tissue disease, dementia, diabetes, HIV/AIDS, hemiplegia, myocardial infarction, liver disease, renal disease, peripheral vascular disease, posterior vitreous detachment, and peptic ulcer disease","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"low","ROB7":"low","ROB8":"low","ROB9":"low","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"NEUROLOGICAL DISORDERS","outcome_disease":"Sensory disorders","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.25,"TE":0.22314,"seTE":0.01531,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":19,"uncertainty_of_confounders":"low","list_of_confounders":"Adjustment through inverse probability weighting using predefined and algorithmically selected high-dimensional variables including age, race, sex, ADI, BMI, smoking status, measures of healthcare utilization number of outpatient and inpatient encounters, as well as long-term care utilization, comorbidities cancer, chronic kidney disease, chronic lung disease, diabetes, and hypertension, eFGR, systolic, and diastolic pressure. Additional several data domains including diagnoses, drugs, and laboratory tests.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"NEUROLOGICAL DISORDERS","outcome_disease":"Cognitive impairment","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.8,"TE":0.58779,"seTE":0.04337,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":19,"uncertainty_of_confounders":"low","list_of_confounders":"Adjustment through inverse probability weighting using predefined and algorithmically selected high-dimensional variables including age, race, sex, ADI, BMI, smoking status, measures of healthcare utilization number of outpatient and inpatient encounters as well as long-term care utilization, comorbidities cancer, chronic kidney disease, chronic lung disease, diabetes, and hypertension, eFGR, systolic, and diastolic pressure. Additional several data domains including diagnoses, drugs, and laboratory tests.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"NEUROLOGICAL DISORDERS","outcome_disease":"Extrapyramidal and other movement disorders","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.42,"TE":0.35066,"seTE":0.04082,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":19,"uncertainty_of_confounders":"low","list_of_confounders":"Adjustment through inverse probability weighting using predefined and algorithmically selected high-dimensional variables including age, race, sex, ADI, BMI, smoking status, measures of healthcare utilization number of outpatient and inpatient encounters as well as long-term care utilization, comorbidities cancer, chronic kidney disease, chronic lung disease, diabetes, and hypertension, eFGR, systolic, and diastolic pressure. Additional several data domains including diagnoses, drugs, and laboratory tests.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"NEUROLOGICAL DISORDERS","outcome_disease":"Other sleep disorders","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.41,"TE":0.34359,"seTE":0.01786,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":22,"uncertainty_of_confounders":"low","list_of_confounders":"Adjustment through predefined and algorithmically selected high-dimensional covariates including age, race, sex, Area Deprivation Index, BMI, smoking status, healthcare utilization measures (number of outpatient encounters, hospital admissions and use of long term care), comorbidities (cancer, chronic kidney disease, chronic lung disease, dementia, diabetes, dysautonomia, hyperlipidaemia, and hypertension), eFGR, systolic, and diastolic blood pressure. Additional several data domains including diagnoses, drugs, and laboratory tests.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"NEUROLOGICAL DISORDERS","outcome_disease":"Peripheral Neuropathy","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.34,"TE":0.29267,"seTE":0.02551,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":19,"uncertainty_of_confounders":"low","list_of_confounders":"Adjustment through inverse probability weighting using predefined and algorithmically selected high-dimensional variables including age, race, sex, ADI, BMI, smoking status, measures of healthcare utilization (number of outpatient and inpatient encounters as well as long-term care utilization), comorbidities (cancer, chronic kidney disease, chronic lung disease, diabetes and hypertension), eFGR, systolic ,and diastolic pressure. Additional several data domains including diagnoses, drugs and, laboratory tests.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"NEUROLOGICAL DISORDERS","outcome_disease":"Headaches and Migraine","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.32,"TE":0.27763,"seTE":0.03316,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":19,"uncertainty_of_confounders":"low","list_of_confounders":"Adjustment through inverse probability weighting using predefined and algorithmically selected high-dimensional variables including age, race, sex, ADI, BMI, smoking status, measures of healthcare utilization (number of outpatient and inpatient encounters as well as long-term care utilization), comorbidities (cancer, chronic kidney disease, chronic lung disease, diabetes and hypertension), eFGR, systolic ,and diastolic pressure. Additional several data domains including diagnoses, drugs, and laboratory tests.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"PSYCHIATRIC DISORDERS","outcome_disease":"Depressive disorders","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.39,"TE":0.3293,"seTE":0.02296,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":22,"uncertainty_of_confounders":"low","list_of_confounders":"Adjustment through predefined and algorithmically selected high-dimensional covariates including age, race, sex, Area Deprivation Index, BMI, smoking status, healthcare utilization measures (number of outpatient encounters, hospital admissions and use of long term care), comorbidities (cancer, chronic kidney disease, chronic lung disease, dementia, diabetes, dysautonomia, hyperlipidaemia, and hypertension), eFGR, systolic and, diastolic blood pressure. Additional several data domains including diagnoses, drugs, and laboratory tests.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"PSYCHIATRIC DISORDERS","outcome_disease":"Anxiety disorder","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.35,"TE":0.3001,"seTE":0.02296,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":22,"uncertainty_of_confounders":"low","list_of_confounders":"Adjustment through predefined and algorithmically selected high-dimensional covariates including age, race, sex, Area Deprivation Index, BMI, smoking status, healthcare utilization measures (number of outpatient encounters, hospital admissions and use of long term care), comorbidities (cancer, chronic kidney disease, chronic lung disease, dementia, diabetes, dysautonomia, hyperlipidaemia, and hypertension), eFGR, systolic and, diastolic blood pressure. Additional several data domains including diagnoses, drugs, and laboratory tests.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"ENDOCRINE AND METABOLIC DISORDERS","outcome_disease":"Diabetes","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.36,"TE":0.30748,"seTE":0.02296,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":34,"uncertainty_of_confounders":"low","list_of_confounders":"Models were weighted for age, race, sex, ADI, the number in the two years prior to enrollment of outpatient visits, inpatient visits, unique medication prescriptions, and routine blood chemistry panels, utilization of Medicare, prior history of receiving an influenza vaccination, smoking status, anxiety, cancer, cardiovascular disease, cerebrovascular disease, chronic kidney disease, dementia, depression, type 2 diabetes mellitus, chronic obstructive pulmonary disease, immunocompromised status, peripheral artery disease, systolic blood pressure, diastolic blood pressure, estimated glomerular filtration rate, body mass index, calendar week of enrollment, geograpahic area of VISN, HHS proportion of Delta variant, average bed capacity and total bed capacity of the attending hospital, number of vaccinations, SARS-CoV-2 treatment, hospitalization and admittance to ICU during the acute phase of the first infection, as well as algorithmically selected high dimensional variables.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"CARDIOVASCULAR DISORDERS","outcome_disease":"All Cardiovascular","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.57,"TE":0.45108,"seTE":0.01786,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":34,"uncertainty_of_confounders":"low","list_of_confounders":"Models were weighted for age, race, sex, ADI, the number in the two years prior to enrollment of outpatient visits, inpatient visits, unique medication prescriptions, and routine blood chemistry panels, utilization of Medicare, prior history of receiving an influenza vaccination, smoking status, anxiety, cancer, cardiovascular disease, cerebrovascular disease, chronic kidney disease, dementia, depression, type 2 diabetes mellitus, chronic obstructive pulmonary disease, immunocompromised status, peripheral artery disease, systolic blood pressure, diastolic blood pressure, estimated glomerular filtration rate, body mass index, calendar week of enrollment, geograpahic area of VISN, HHS proportion of Delta variant, average bed capacity and total bed capacity of the attending hospital, number of vaccinations, SARS-CoV-2 treatment, hospitalization and admittance to ICU during the acute phase of the first infection, as well as algorithmically selected high dimensional variables.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"HEMATOLOGICAL DISORDERS AND IMMUNE DISORDERS","outcome_disease":"Coagulopathy","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.64,"TE":0.4947,"seTE":0.02551,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":34,"uncertainty_of_confounders":"low","list_of_confounders":"Models were weighted for age, race, sex, ADI, the number in the two years prior to enrollment of outpatient visits, inpatient visits, unique medication prescriptions, and routine blood chemistry panels, utilization of Medicare, prior history of receiving an influenza vaccination, smoking status, anxiety, cancer, cardiovascular disease, cerebrovascular disease, chronic kidney disease, dementia, depression, type 2 diabetes mellitus, chronic obstructive pulmonary disease, immunocompromised status, peripheral artery disease, systolic blood pressure, diastolic blood pressure, estimated glomerular filtration rate, body mass index, calendar week of enrollment, geograpahic area of VISN, HHS proportion of Delta variant, average bed capacity and total bed capacity of the attending hospital, number of vaccinations, SARS-CoV-2 treatment, hospitalization and admittance to ICU during the acute phase of the first infection, as well as algorithmically selected high dimensional variables.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"PSYCHIATRIC DISORDERS","outcome_disease":"Any psychiatric disorder","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.29,"TE":0.25464,"seTE":0.00765,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":34,"uncertainty_of_confounders":"low","list_of_confounders":"Models were weighted for age, race, sex, ADI, the number in the two years prior to enrollment of outpatient visits, inpatient visits, unique medication prescriptions, and routine blood chemistry panels, utilization of Medicare, prior history of receiving an influenza vaccination, smoking status, anxiety, cancer, cardiovascular disease, cerebrovascular disease, chronic kidney disease, dementia, depression, type 2 diabetes mellitus, chronic obstructive pulmonary disease, immunocompromised status, peripheral artery disease, systolic blood pressure, diastolic blood pressure, estimated glomerular filtration rate, body mass index, calendar week of enrollment, geograpahic area of VISN, HHS proportion of Delta variant, average bed capacity and total bed capacity of the attending hospital, number of vaccinations, SARS-CoV-2 treatment, hospitalization and admittance to ICU during the acute phase of the first infection, as well as algorithmically selected high dimensional variables.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"RENAL DISORDERS","outcome_disease":"Acute kidney injury","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.39,"TE":0.3293,"seTE":0.02296,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":34,"uncertainty_of_confounders":"low","list_of_confounders":"Models were weighted for age, race, sex, ADI, the number in the two years prior to enrollment of outpatient visits, inpatient visits, unique medication prescriptions, and routine blood chemistry panels, utilization of Medicare, prior history of receiving an influenza vaccination, smoking status, anxiety, cancer, cardiovascular disease, cerebrovascular disease, chronic kidney disease, dementia, depression, type 2 diabetes mellitus, chronic obstructive pulmonary disease, immunocompromised status, peripheral artery disease, systolic blood pressure, diastolic blood pressure, estimated glomerular filtration rate, body mass index, calendar week of enrollment, geograpahic area of VISN, HHS proportion of Delta variant, average bed capacity and total bed capacity of the attending hospital, number of vaccinations, SARS-CoV-2 treatment, hospitalization and admittance to ICU during the acute phase of the first infection, as well as algorithmically selected high dimensional variables.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"CARDIOVASCULAR DISORDERS","outcome_disease":"All Cardiovascular","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.51,"TE":0.41211,"seTE":0.02806,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":31,"uncertainty_of_confounders":"low","list_of_confounders":"Models were weighted for age, race, ADI, the number in the two years prior to enrollment of outpatient visits, inpatient visits, unique medication prescriptions, and routine blood chemistry panels, body mass index (BMI), prior history of receiving an influenza vaccination, smoking status, anxiety, cancer, cardiovascular disease, cerebrovascular disease, chronic kidney disease, dementia, depression, type 2 diabetes mellitus, chronic obstructive pulmonary disease, and peripheral artery disease, systolic blood pressure, diastolic blood pressure, estimated glomerular filtration rate, and hospital system average hospital bed occupancy, total hospital bed capacity, positivity rate of tests, number of tests, and HHS region SARS-CoV-2 variant proportion in the week prior to enrollment, geographic region of VISN, and calendar week of enrollment, as well as algorithmically selected high dimensional variables.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"PSYCHIATRIC DISORDERS","outcome_disease":"Any psychiatric disorder","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.43,"TE":0.35767,"seTE":0.02296,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":18,"uncertainty_of_confounders":"low","list_of_confounders":"Adjustment through inverse probability weighting using predefined and algorithmically selected high-dimensional variables including age, race, sex, ADI, BMI, smoking status, measures of healthcare utilization (number of outpatient and inpatient encounters as well as long-term care utilization), comorbidities (cancer, chronic kidney disease, chronic lung disease, diabetes, and hypertension), eFGR, systolic, and diastolic pressure. Additional several data domains including diagnoses, drugs and laboratory tests.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"HEMATOLOGICAL DISORDERS AND IMMUNE DISORDERS","outcome_disease":"Coagulopathy","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":2.21,"TE":0.79299,"seTE":0.08929,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":31,"uncertainty_of_confounders":"low","list_of_confounders":"Models were weighted for age, race, ADI, the number in the two years prior to enrollment of outpatient visits, inpatient visits, unique medication prescriptions, and routine blood chemistry panels, body mass index (BMI), prior history of receiving an influenza vaccination, smoking status, anxiety, cancer, cardiovascular disease, cerebrovascular disease, chronic kidney disease, dementia, depression, type 2 diabetes mellitus, chronic obstructive pulmonary disease, and peripheral artery disease, systolic blood pressure, diastolic blood pressure, estimated glomerular filtration rate, and hospital system average hospital bed occupancy, total hospital bed capacity, positivity rate of tests, number of tests, and HHS region SARS-CoV-2 variant proportion in the week prior to enrollment, geographic region of VISN, and calendar week of enrollment, as well as algorithmically selected high dimensional variables.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"RENAL DISORDERS","outcome_disease":"Acute kidney injury","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.49,"TE":0.39878,"seTE":0.03061,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":31,"uncertainty_of_confounders":"low","list_of_confounders":"Models were weighted for age, race, ADI, the number in the two years prior to enrollment of outpatient visits, inpatient visits, unique medication prescriptions, and routine blood chemistry panels, body mass index (BMI), prior history of receiving an influenza vaccination, smoking status, anxiety, cancer, cardiovascular disease, cerebrovascular disease, chronic kidney disease, dementia, depression, type 2 diabetes mellitus, chronic obstructive pulmonary disease, and peripheral artery disease, systolic blood pressure, diastolic blood pressure, estimated glomerular filtration rate, and hospital system average hospital bed occupancy, total hospital bed capacity, positivity rate of tests, number of tests, and HHS region SARS-CoV-2 variant proportion in the week prior to enrollment, geographic region of VISN, and calendar week of enrollment, as well as algorithmically selected high dimensional variables.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Al-Aly 2022","category":"PSYCHIATRIC DISORDERS","outcome_disease":"Any substance use disorders","data_source":"Health Records","sample_size":6280559,"effect_type":"HR","effect":1.2,"TE":0.18232,"seTE":0.02806,"follow_up_time":50,"mean_age":61,"reinfection":"yes","disease_severity":"yes","no_of_confounders":20,"uncertainty_of_confounders":"low","list_of_confounders":"Adjustment through predefined and algorithmically selected high-dimensional covariates including age, race, sex, Area Deprivation Index, BMI, smoking status, healthcare utilization measures number of outpatient encounters, hospital admissions and use of long term care, cancer, chronic kidney disease, chronic lung disease, dementia, diabetes, dysautonomia, hyperlipidaemia and hypertension, eFGR, systolic and, diastolic blood pressure. Additional several data domains including diagnoses, drugs, and laboratory tests.","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"unclear","ROB10":"high","ROB11":"low"} {"study":"Amin-Chowdhury 2021","category":"NEUROLOGICAL DISORDERS","outcome_disease":"Sensory disorders","data_source":"Survey","sample_size":1300,"effect_type":"OR","effect":5.25,"TE":1.65823,"seTE":1.16326,"rate_control":0.11897,"follow_up_time":14,"mean_age":42,"reinfection":"no","disease_severity":"no","no_of_confounders":5,"uncertainty_of_confounders":"low","list_of_confounders":"age, sex, comorbidity, ethnicity, workplace role","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"low","ROB10":"unclear","ROB11":"high"} {"study":"Ayoubkhani 2021","category":"CARDIOVASCULAR DISORDERS","outcome_disease":"All Cardiovascular","data_source":"Health Records","sample_size":95560,"effect_type":"RR","effect":4.97,"TE":1.60416,"seTE":0.07985,"rate_control":0.00526,"follow_up_time":20,"mean_age":65,"reinfection":"no","disease_severity":"yes","no_of_confounders":13,"uncertainty_of_confounders":"low","list_of_confounders":"age, sex, ethnicity, region, Index of Multiple Deprivation quintile, smoking status) and comorbidites hypertension, major adverse cardiovascular event, respiratory disease, chronic kidney disease, chronic liver disease, diabetes, cancer","ROB1":"low","ROB2":"low","ROB3":"low","ROB4":"low","ROB5":"low","ROB6":"unclear","ROB7":"low","ROB8":"low","ROB9":"low","ROB10":"unclear","ROB11":"low"} {"study":"Ayoubkhani 2021","category":"ENDOCRINE AND METABOLIC DISORDERS","outcome_disease":"Diabetes","data_source":"Health 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